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Open Federal Grants · National Institutes of Health

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

National Institutes of Health · Opportunity PAR-25-101 · Awards up to $150,000

AgencyNational Institutes of Health
Opportunity NumberPAR-25-101
Award FloorNot stated in the listing
Award Ceiling$150,000
Cost Sharing / MatchingNot required by the listing
Application DeadlineAug 11, 2027 — 301 days left as of Oct 14, 2026
Last Updated on Grants.govMar 31, 2025
Who Can ApplyState governments, County governments, City / township governments, Regional organizations, U.S. territories & freely associated states, Independent school districts, Federally recognized tribal governments, Public housing authorities, Native American tribal organizations, Nonprofits with 501(c)(3) status, Nonprofits without 501(c)(3) status, Private colleges / universities, For-profit organizations, Small businesses, Other applicants

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-b

Eligibility text quoted from the official Grants.gov listing.

About This Opportunity

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary …

Description from the official Grants.gov listing — read the complete notice, including any updates, on Grants.gov before applying.

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Browse Open Grants

By who can apply:

Nonprofits 856Small Businesses 756State Governments 848Local & Regional Governments 821Tribal Governments & Organizations 851Schools, Colleges & Universities 865Individuals 14Open to All Applicant Types 187

By agency:

NIH 673National Science Foundation 104FDA 54CDC 52HRSA 49Defense Health Agency 47Bureau of Justice Assistance 24Indian Health Service 18NASA Headquarters 16Office of Juvenile Justice Delinquency Prevention 16HUD 15Administration for Community Living 15All agencies & the full hub →

By closing month:

October 2026 102November 2026 145December 2026 54January 2027 62February 2027 23March 2027 18April 2027 22

Every grant listed here comes from Grants.gov, the official U.S. government database. Award amounts and deadlines can change — verify the details on the official listing before you apply. GrantRound is not affiliated with the U.S. government.