GrantRound

Open Federal Grants · National Institutes of Health

Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

National Institutes of Health · Opportunity PAR-27-011 · Award amount: see the official listing

Opportunity NumberPAR-27-011
Award FloorNot stated in the listing
Award CeilingNot stated in the listing
Cost Sharing / MatchingNot required by the listing
Application DeadlineNov 2, 2028
Last Updated on Grants.govMar 18, 2026
Who Can ApplyState governments, County governments, City / township governments, Regional organizations, U.S. territories & freely associated states, Independent school districts, Federally recognized tribal governments, Public housing authorities, Native American tribal organizations, Nonprofits with 501(c)(3) status, Nonprofits without 501(c)(3) status, Private colleges / universities, For-profit organizations, Small businesses, Other applicants

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domesti

Eligibility text quoted from the official Grants.gov listing.

About This Opportunity

This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct investigator-initiated single site clinical trials including efficacy, comparative effectiveness, pragmatic and/or dissemination and implementation science clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, dissemination and implementation science clinical trials and/ …

Description from the official Grants.gov listing — read the complete notice, including any updates, on Grants.gov before applying.

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