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Open Federal Grants · National Institutes of Health

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity RFA-DC-27-004 · Awards up to $700,000

Opportunity NumberRFA-DC-27-004
Award FloorNot stated in the listing
Award Ceiling$700,000
Cost Sharing / MatchingNot required by the listing
Application DeadlineFeb 11, 2027 — 120 days left as of Oct 14, 2026
Last Updated on Grants.govMay 4, 2026
Who Can ApplyState governments, County governments, City / township governments, Regional organizations, U.S. territories & freely associated states, Independent school districts, Federally recognized tribal governments, Public housing authorities, Native American tribal organizations, Nonprofits with 501(c)(3) status, Nonprofits without 501(c)(3) status, Private colleges / universities, For-profit organizations, Small businesses, Other applicants

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-do

Eligibility text quoted from the official Grants.gov listing.

About This Opportunity

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensation …

Description from the official Grants.gov listing — read the complete notice, including any updates, on Grants.gov before applying.

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