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Open Federal Grants · Food and Drug Administration

Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)

Food and Drug Administration · Opportunity RFA-FD-25-017 · Awards up to $600,000

Opportunity NumberRFA-FD-25-017
Award FloorNot stated in the listing
Award Ceiling$600,000
Cost Sharing / MatchingNot required by the listing
Application DeadlineFeb 8, 2028
Last Updated on Grants.govJul 11, 2025
Who Can ApplyOther applicants

Eligibility

Eligible OrganizationsHigher Education InstitutionsPublic/State Controlled Institutions of Higher EducationPrivate Institutions of Higher EducationNonprofits Other Than Institutions of Higher EducationNonprofits with 501(c)(3) IRS Status (O

Eligibility text quoted from the official Grants.gov listing.

About This Opportunity

The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with simi …

Description from the official Grants.gov listing — read the complete notice, including any updates, on Grants.gov before applying.

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