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Open Federal Grants · National Institutes of Health

Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

National Institutes of Health · Opportunity RFA-HG-27-007 · Awards up to $2,000,000

Opportunity NumberRFA-HG-27-007
Award FloorNot stated in the listing
Award Ceiling$2,000,000
Cost Sharing / MatchingNot required by the listing
Application DeadlineDec 14, 2026 — 61 days left as of Oct 14, 2026
Last Updated on Grants.govOct 9, 2026
Who Can ApplyState governments, County governments, City / township governments, Regional organizations, U.S. territories & freely associated states, Independent school districts, Federally recognized tribal governments, Public housing authorities, Native American tribal organizations, Nonprofits with 501(c)(3) status, Nonprofits without 501(c)(3) status, Private colleges / universities, For-profit organizations, Small businesses, Other applicants

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non

Eligibility text quoted from the official Grants.gov listing.

About This Opportunity

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing robust, reproducible, and portable data processing …

Description from the official Grants.gov listing — read the complete notice, including any updates, on Grants.gov before applying.

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